Table 3.
Systemic and ocular parameters before and after topical application of nipradilol in normal-tension glaucoma.
| Parameter | Before | 2 hrs (P) | 4 weeks (P) |
|---|---|---|---|
| Intraocular pressure (mmHg) | 15.3 ± 2.2 | 13.7 ± 2.2 (0.0004)* | 14.0 ± 1.3 (0.0052)* |
| Blood pressure | |||
| Systolic (mmHg) | 130.0 ± 19.2 | 131.0 ± 21.7 (0.6456) | 129.0 ± 19.8 (0.7206) |
| Diastolic (mmHg) | 78.7 ± 13.4 | 81.2 ± 11.8 (0.1363) | 77.7 ± 11.6 (0.5139) |
| Heart rate (beats/min) | 71.4 ± 11.9 | 65.7 ± 11.7 (0.0067)* | 68.1 ± 13.6 (0.3316) |
| Ocular perfusion pressure (mmHg) | 48.6 ± 9.2 | 51.5 ± 8.8 (0.0002)* | 49.2 ± 8.8 (0.4443) |
Wilcoxon signed-rank sum test.
Values are presented as mean ± standard deviation.
(P)* < 0.05.