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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Antiviral Res. 2011 Sep 8;92(2):329–340. doi: 10.1016/j.antiviral.2011.09.001

Figure 2.

Figure 2

Effects of 2’FdC administered per os on survival and weight change of female BALB/c mice infected with a lethal dose of avian influenza A/Vietnam/1203/2004 H5N1 virus.

A. Survival of infected BALB/c mice treated with PSS (●), 2’FdC at 30 (■), 3.0 (▲), 0.3 (▼) mg/kg/day, or ribavirin at 75 mg/kg/day (♦) twice a day for 8 days (bid × 8). ** P<0.01, ribavirin versus PSS. A. Survival of infected BALB/c mice treated with PSS (●), 2’FdC at 30 (■), 3.0 (▲), 0.3 (▼) mg/kg/day, or ribavirin at 75 mg/kg/day (♦) (bid × 8), beginning −24 h relative to virus exposure. ** P<0.01, ribavirin versus water.

B. Weight change through day 13 in Infected BALB/c mice treated with PSS (●), 2’FdC at 30 (■), 3.0 (▲), 0.3 (▼) mg/kg/day, or ribavirin at 75 mg/kg/day (♦) (bid × 8), beginning −24 h relative to virus exposure.