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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Antiviral Res. 2011 Sep 8;92(2):329–340. doi: 10.1016/j.antiviral.2011.09.001

Table 4.

Effects of 2'-FdC Treatment of BALB/c Mice Infected with Influenza/A/Vietnam/1203/2004 H5N1 Virus on Various Lung Parameters at Day 4 Post Virus Exposure

Treatment Lung Score
± SDa
Lung WeightSD
± SDa
Virus Lung Titers
± SD (Log10/g)a
0.4% CMC 0.4 ± 0.22 0.17 ± 0.011 4.10 ± 1.052
2'-FDC (60 mg/kg/d) 0.4 ± 0.25 0.14 ± 0.014 3.60 ± 1.303
2'-FDC (30 mg/kg/d) 0.2 ± 0.27 0.13 ± 0.012* 4.01 ± 0.713
Ribavirin (75 mg/kg/d) 0.6 ± 0.13 0.12 ± 0.014** 1.42 ± 0.000**
a

Values represent the arithmetic the standard deviation.

*

P<0.05,

**

P<0.01 vs. 0.4% CMC treatment group by ANOVA and Newman-Keuls pairwise comparison test.