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. 2006 Feb 28;94(6):806–813. doi: 10.1038/sj.bjc.6602975

Table 2. Dose modifications due to haematological toxicity, cycle 2 onwards.

Platelet count × 109 l−1 Neutrophil count × 109 l−1 Dose adjustment for CHOP Dose adjustment for PMitCEBO
100+ >1.5 100% 100%
75–99 1.0 75% cyclophosphamide, doxorubicin 100%
50–74 0.5–1.0 50% cyclophosphamide, doxorubicin 65% cyclophosphamide, mitoxantrone, etoposide
    100% vincristine 100% vincristine, bleomycin
<50 <0.5 Delay all drugs for 1 week Delay all drugs for 1 week