Figure 2. CD14⁺ cells promote angiogenesis and recruit endogenous proangiogenic cells in hypoxic areas (A) At P12 the obliteration area in CD14⁺ treated eyes is reduced by 50% compared to vehicle-treated retinas (n = 8, n = number of eyes for each condition).

(B) Lectin-positive cells in areas of vaso-obliteration are increased 2.2- fold after intravitreal injection of CD14⁺ cells relative to vehicle injection (n = 6, n = number of eyes for each condition) (*P <0.001 Bonferroni corrected t-test). (C) 10x confocal images of retinas treated with CD14⁺ shows high recruitment of lectin-positive cells with microglial-like morphology. (D) Lectin-positive cells are absent in vehicle-injected retinas.