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. 2011 Nov 8;1:147. doi: 10.1038/srep00147

Figure 8. Probing cell-substrate interactions of cells stimulated by shear fluid flow through high-resolution confocal imaging.

Figure 8

Z-stacks (0.5 μm steps) of sheared cells were taken to analyze FN response. A top view displays substrate FN (A) cellular fibronectin (B) DAPI (C) and a merged image (D) of all structures, and a merged side view (E). Mechanically stimulated cells were observed to have a more structurally dense FN matrix compared to unstimulated while the substrate FN was observed to be structurally modified in response to mechanical stimulation. (scale bars = 5 μm).