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. 2011 Nov 15;22(22):4236–4246. doi: 10.1091/mbc.E11-03-0216

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© 2011 Hagan et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 4: — p31^comet acts downstream of the timer functions of Mad2 but upstream of kinetochore functions. (A) Mitotic arrest of HeLa Histone 2B-GFP cells was measured as in Figure 1B. Bars indicate mean and range of at least two independent experiments. (B and C) Cumulative frequency graphs of anaphase times in cells treated with siRNA as indicated. Dashed lines for control RNAi and p31^comet/control RNAi are identical between B and C.