TABLE 1:

Species concentrations used in simulations.

Species	Concentration	Initial condition
Total Mad2 (m2c, m2o)	120 nM	All Mad2-O
Kinetochore (Km2c)	1 nM	Constitutive
p31comet (p)	Adjusted	0 nM
APC/C (a)	90 nM	Active APC/C