FIG. 1.

Kinetics of circulating α- and β-linked mannoglycoconjugates as detected by MAb EB-CA1 (Platelia Ag) or MAb 5B2 (EIA 5B2) (boxes with or without • symbols, respectively) in sequentially drawn serum samples from guinea pigs experimentally infected by two strains of C. albicans. For each test, the levels of α- and β-mannanemia were graded from minimal (mannanemia levels of <0.1 ng/ml [white boxes]) to peak (mannanemia levels of ≥1 ng/ml [black boxes]) on the basis of the detected mannan concentrations; intermediate values are represented by light-grey box shading (mannanemia levels between ≤0.1 ng/ml and <0.5 ng/ml) or dark-grey box shading (mannanemia levels between ≤0.5 ng/ml and <1 ng/ml). nd, tests not done; †, deceased animals.