Table 4.
Effects of respiratory function tests (values dichotomized) on the change in VC in pirfenidone and placebo groups
| Group | Parameter | Estimate | S.E. | t-value | p-value |
|---|---|---|---|---|---|
| Pirfenidone | Intercept | -0.0857 | 0.0523 | -1.64 | 0.1039 |
| (n = 155) | The lowest SpO2: <90 vs ≥90 | -0.0090 | 0.0381 | -0.24 | 0.8133 |
| %VC: <70 vs ≥70 | 0.1447 | 0.0386 | 3.75 | 0.0002 | |
| PaO2: <70 vs ≥70 | -0.1111 | 0.0558 | -1.99 | 0.0483 | |
| Placebo | Intercept | -0.1196 | 0.0923 | -1.30 | 0.1982 |
| (n = 103) | The lowest SpO2: <90 vs ≥90 | 0.0628 | 0.0566 | 1.11 | 0.2701 |
| %VC: <70 vs ≥70 | 0.0302 | 0.0585 | 0.52 | 0.6067 | |
| PaO2: <70 vs ≥70 | -0.0977 | 0.0878 | -1.11 | 0.2685 | |