Table 2.

Comparisons between H3K27me3 target genes in colon tissue samples and CRC cell lines.

			Patient 1		Patient 2		Cell Lines
			Normal	Tumor	Normal	Tumor	HT29	SW480
			K27	K27	K27	K27	K27	SUZ12
Patient 1	Normal	K27	600	310	399	237	138	74
	Tumor	K27		660	349	242	164	88
Patient 2	Normal	K27			636	282	154	84
	Tumor	K27				512	151	82
Cell Lines	HT29	K27					512	67
	SW480	SUZ12						447

The different gene categories considered (in bold) consisted of the genes marked by H3K27me3 in normal or tumor samples from patient 1 or patient 2, genes bound by H3K27me3 in HT29 CRC cell line and genes bound by SUZ12 in SW480 CRC cell line. Only genes were both H3K27me3 data in tissues samples and HT29 cell line and SUZ12 data in SW480 cell line were available were considered (total = 7393), which was limited by the coverage of the arrays used. The numbers in the diagonal of the table (in bold) indicate all genes included in each category, while the remaining numbers indicate the overlaps between each pair of categories considered in each case.