TABLE 2.
Mutations in the mpb64 gene of the Capilia TB-negative M. tuberculosis isolates from Japan
| Mutation positiona | Mutation | No. of isolates | Place of isolation (n) |
|---|---|---|---|
| 196 | 63-bp deletion | 3 | Tokyo (2), Fukuoka (1) |
| 266 | C deletion | 1 | Tokyo (1) |
| 402 | G→A mutation | 2 | Tokyo (2) |
| 501 | IS6110 insertion (1,358 bp) | 1 | Fukuoka (1) |
| 512 | 872-bp deletion | 5 | Hokkaido (1), Osaka (2) Kyoto (1), Hiroshima (1) |
a
The DNA sequence contained an open reading frame starting with translation initiation codon GTG at nucleotide positions 1 to 3 and ending with termination codon TAG at positions 685 to 687 (20).