Table 4. Pooled crude and adjusted seasonal vaccine effectiveness against all influenza, A(H1N1)2009 and influenza B, overall and by age group, imputed data, I-MOVE multi-centre case control study, influenza season 2010-11.
| Outcome | N | VE % | 95% CI | ||
| All influenza | All ages | Crude‡ | 4410 | 64.2 | 53.2-72.6 |
| Adjusted model∫ | 4410 | 51.9 | 30.0-66.9 | ||
| 0-14 years1 | Crude‡ | 1422 | 50.5 | -4.2-76.5 | |
| Adjusted model∫ | 1422 | 65.7 | 15.4-86.1 | ||
| 15-59 years2 | Crude‡ | 2509 | 56.5 | 31.2-72.6 | |
| Adjusted model∫ | 2509 | 41.3 | -2.6-66.4 | ||
| 60+ years3 | Crude‡ | 464 | 55.2 | 29.0-71.7 | |
| Adjusted model∫ | 464 | 59.9 | 16.7-80.7 | ||
| A(H1N1)2009 | All ages | Crude‡ | 3344 | 67.9 | 54.6-77.3 |
| Adjusted model∫ | 3344 | 55.5 | 28.7-72.2 | ||
| 0-14 years4 | Crude‡ | 910 | 63.1 | -10.6-87.7 | |
| Adjusted model∫ | 910 | 77.2 | 16.0-93.8 | ||
| 15-59 years5 | Crude‡ | 2051 | 41.4 | 1.7-65.1 | |
| Adjusted model∫ | 2051 | 27.2 | -37.1-61.4 | ||
| 60+ years6 | Crude‡ | 350 | 72.5 | 47.7-85.5 | |
| Adjusted model∫ | 350 | 72.3 | 26.5-89.6 | ||
| Influenza B | All ages | Crude‡ | 2944 | 65.8 | 49.4-76.9 |
| Adjusted model∫ | 2944 | 49.8 | 13.8-70.8 | ||
| 0-14 years7 | Crude‡ | 1067 | 45.5 | -30.1-77.2 | |
| Adjusted model∫ | 1067 | 62.9 | -6.4-87.1 | ||
| 15-59 years8 | Crude‡ | 1502 | 74.6 | 38.4-89.6 | |
| Adjusted model∫ | 1502 | 63.7 | -3.9-87.4 | ||
| 60+ years9 | Crude‡ | 345 | 47.6 | -1.6-72.9 | |
| Adjusted model∫ | 345 | 55.5 | -37.9-85.6 |
Study site included in the model as fixed effect.
Model adjusted for 2009-10 seasonal and pandemic influenza vaccination, presence of at least one chronic disease, sex, at least one hospitalisation for chronic disease in the previous 12 months, current smoker, age group (10 year bands), practitioner visits in previous 12 months (0-1, 2-4 and 5+ visits), week of symptom onset.
NB: For influenza B imputed analysis, we are obliged to drop week 14 (1 record) in order to do computation.
For the certain analyses, weeks of onset had to be dropped due to only positive or negative outcomes during this week.
Weeks 13 and 14 dropped (8 records dropped).
Week 14 dropped (2 records dropped).
Weeks 46 and 14 dropped (5 records dropped).
Weeks 12, 13 and 14 dropped (8 records dropped).
Week 14 dropped (1 record dropped).
Weeks 48,49 and 10-14 dropped (28 records dropped).
Week 13 dropped (4 records dropped).
Week 49 dropped (14 records dropped).
Weeks 46 and 50 dropped (14 records dropped).