Table 1. Clinical scores and occurrence.
Occurrence | Onset | Peak score | AUC | |
C57BL/6 | ||||
R037 | 18/18 (100%) | 13.1±0.6 | 3.6±0.3* | 19.6±3.1* |
control | 17/17 (100%) | 13.0±0.5 | 4.9±0.3 | 30.4±3.4 |
SJL/J | ||||
R037 | 13/16 (81%) | 13.1±0.4** | 1.5±0.2* | 8.4±1.4* |
control | 15/17 (88%) | 11.5±0.2 | 2.9±0.4 | 15.2±2.2 |
Data are reported as mean ± SEM. The means of the peak and the area under the curve (AUC) represent data during days 1 to 21 after immunization. Data are representative of two independent experiments in C57BL/6 and SJL/J mice.
*p≤0.05;
**p≤0.01 (t-test).