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. 2011 Nov 15;6(11):e27629. doi: 10.1371/journal.pone.0027629

Figure 2. Strain-dependent decreased abundance of CD11c+ cells in the BAL of naive IL-19-/- 129xBL6 mice.

Figure 2

The abundance of CD11c+ cells in the BAL (%) from individual mice is shown for the following parental and offspring strains: (A) IL-19-/- 129xBL6 (blue diamonds); IL-19-/- C57BL/6 (yellow upright triangles); second generation, intercross F2 offspring from a cross between IL-19-/- 129xBL6 and IL-19-/- C57BL/6 parental lines (green circles); and for comparison, wild-type C57BL/6 (red squares). (B) Backcross N2 offspring originating from a cross between IL-19-/- 129xBL6 and wild-type C57BL/6 mice. The mice were genotyped and found to be wild type (il19 +/il19 + purple squares), heterozygous (il19 +/il19 - yellow downward triangles) or IL-19-/- (il19 -/il19 - blue diamonds). Data from individual mice are shown. Horizontal lines indicate means. Data were pooled from 4-6 experiments. Statistical analysis was with ANOVA followed by Dunnett multiple comparison test, * p<0.05 for comparison between N2-wild type and N2-IL-19 -/-.