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. Author manuscript; available in PMC: 2011 Nov 15.
Published in final edited form as: J Proteome Res. 2010 Aug 6;9(8):4053–4060. doi: 10.1021/pr1002559

Figure 5.

Figure 5

Human plasma protein structures through identification of disulfide bonds in the degradation products. (A) Vitronectin dimer is formed by a Cys-Cys disulfide bond that linked the C terminal regions of the two protein molecules. (B) Antithrombin inhibitor inhibitory site degrades together with other sequence. (C) Plasminogen activation peptide degrades on the outside sequence of the disulfide bonds-linked sequence loop. (D) The protein state during degradation can be uncovered through identification of disulfide bond(s). Descriptions are detailed in the text.