Table 2.

Pathway analysis of genes differentially expressed in primary TLR2 KO versus WT microglia in response to intact S. aureus

Pathways increased in TLR2 WT microglia
GO term	GO ID
Inflammatory response	GO:0006954
Protein sumoylation	GO:0016925
Immune response	GO:0006955
GTPase activity	GO:0003924
GTP binding	GO:0005525
Cell motility	GO:0006928
Positive regulation of apoptosis	GO:0043065
Clathrin adaptor complex	GO:0030131
Diacylglycerol binding	GO:0019992
LPS-mediated signaling pathway	GO:0031663
Response to LPS	GO:0032496
Leukotriene biosynthetic process	GO:0019370
Protein serine/threonine kinase activity	GO:0004674
Clathrin coated vesicle	GO:0030136

Pathways increased in TLR2 KO microglia
GO term	GO ID
Negative regulation of signal transduction	GO:0009968
Myeloid dendritic cell differentiation	GO:0002284