Table 6.

Adjusted mean (SE) mean arterial pressure (MAP), according to trimester and history of migraine, after stratification by overweight status

	First Trimester		Second Trimester		Third Trimester
All Women (N = 3,733)
Migraine	1 Adjusted Mean [SE]	Δ (95% CI)	1 Adjusted Mean [SE]	Δ (95% CI)	1 Adjusted Mean [SE]	Δ (95% CI)
NO	82.42 [0.16]		81.97 [0.11]		84.83 [0.13]
YES	83.30 [0.33]	0.88 (0.3 to 1.5)	82.24 [0.27]	0.27 (−0.2 to 0.8)	87.78 [0.29]	2.95 (2.4 to 3.5)
Lean Women (BMI < 25 kg/m2) (N = 2,584)
Migraine	2 Adjusted Mean [SE]	Δ (95% CI)	2 Adjusted Mean [SE]	Δ (95% CI)	2 Adjusted Mean [SE]	Δ (95% CI)
NO	82.41 [0.17]		81.92 [0.12]		84.80 [0.14]
YES	83.08 [0.39]	0.67 (−0.1 to 1.4)	82.05 [0.30]	0.13 (−0.5 to 0.7)	87.60 [0.33]	2.80 (2.1 to 3.5)
Overweight Women (BMI ≥ 25 kg/m2) (N = 789)
Migraine	3 Adjusted Mean [SE]	Δ (95% CI)	3 Adjusted Mean [SE]	Δ (95% CI)	3 Adjusted Mean [SE]	Δ (95% CI)
NO	87.69 [0.35]		87.30 [0.22]		90.18 [0.27]
YES	89.24 [0.69]	1.55 (0.4 to 2.7)	88.03 [0.58]	0.73 (−0.4 to 1.9)	93.61[0.60]	3.43 (2.3 to 4.6)

¹Adjusted for age, race/ethnicity, parity, and smoking. Adjusted mean values reported are from a regression model based on the entire study cohort (N = 3,733) with indicators variables specified to represent Non-Hispanic white, nulliparous, non-smoking women 25–34 years of age.

²Adjusted for age, race/ethnicity, parity, and smoking. Adjusted mean values reported are from a regression model based on lean women only (N = 2,584) with indicators variables specified to represent Non-Hispanic white, nulliparous, non-smoking women 25–34 years of age, with a pre-pregnancy BMI <25 kg/m²

³Adjusted for age, race/ethnicity, parity, and smoking. Adjusted mean values reported are from a regression model based on overweight women only (N= 789) with indicators variables specified to represent Non-Hispanic white, nulliparous, non-smoking, women 25–34 years of age, with a pre-pregnancy BMI ≥ 25 kg/m²