. Author manuscript; available in PMC: 2013 Jul 1.

Published in final edited form as: J Shoulder Elbow Surg. 2011 Aug 10;21(7):847–858. doi: 10.1016/j.jse.2011.05.004

Table 1.

Grading of H & E stained histology for rat rotator cuff muscles

8 weeks
Groups	Muscle	Adipocytes (grade 0–3)^*	Atrophy (grade 0–4)^†	Endomysial inflammatory cells (grade 0–3)^§
Normal	Supraspinatus	0	0	0
Normal	Infraspinatus	0	0	0
SS Tenotomy	Supraspinatus	0	0	0
SS Tenotomy	Infraspinatus	0	0	0
SS/IS Tenotomy	Supraspinatus	0	0	0
SS/IS Tenotomy	Infraspinatus	0	0.8	0
SS/IS Neurotomy	Supraspinatus	0	1.6	0.8
SS/IS Neurotomy	Infraspinatus	0.6	2	0.8
16 weeks
Groups	Muscle	Adipocytes (grade 0–3)^*	Atrophy (grade 0–4)^†	Endomysial inflammatory cells (grade 0–3)^§
Normal	Supraspinatus	0	0	0
Normal	Infraspinatus	0	0	0
SS Tenotomy	Supraspinatus	0	1.2	0.4
SS Tenotomy	Infraspinatus	0	0	0
SS/IS Tenotomy	Supraspinatus	0	1	0.6
SS/IS Tenotomy	Infraspinatus	0.4	1.7	0.5
SS/IS Neurotomy	Supraspinatus	0	1.4	0.5
SS/IS Neurotomy	Infraspinatus	1.3	2.6	1.6

Adipocytes grading: Grade 0 = no adipocyte, 1 = a few (< 5 in the entire field), 2 = some (5 to 20), 3 = many (> 20)

^†

Atrophy grading: Grade 0 = no atrophy, 1 = minimal atrophy, 2 = mild atrophy, 3 = moderate atrophy, 4 = severe atrophy

^§

Endomysial inflammatory cell grading: Grade 0 = no inflammatory cell, 1 = some, 2 = many, 3 = numerous

Data are shown as the means of the two investigators’ grading scores.