TABLE 1.

Overall interpretive agreement between results of the fluconazole 48-h disk diffusion susceptibility test and of the standard 72-h BMD reference MIC test for 276 C. neoformans isolates

Methoda	% of isolates by categoryb			% of discrepant resultsc			% Categorical agreementd
	S	S-DD	R	Minor	Major	Very major
BMD	93.8	5.8	0.4
Disk	87.3	8.3	4.4	12.0	2.0	0	86

^aThe BMD method was used according to the guidelines for the NCCLS M27-A2 method (16). The disk method was used according to the guidelines for the NCCLS M44-P method (17).

^bPercentage of isolates classified in the different susceptibility categories. See Materials and Methods for definitions.

^cPercentage of test results with minor, major, or very major discrepancies compared to the results of the reference BMD method at 72 h. See Materials and Methods for definitions.

^dAgreement rates reflect the percentage of isolates classified in the same category by both the disk and the reference BMD methods.