Table 3.
Week 0 | Week 1 | Week 2 | Week 3 (last injection) | Week 4 | |
---|---|---|---|---|---|
ALT (U/L) | 15.8 (7.5) | 18.8 (9.3) | 19.3 (9.1) | 19.3 (6.8) | 18.6 (6.1) |
AST (U/L) | 183.5 (16.1) | 197.8 (44.8) | 217.6 (52.5) | 276 (170.5) | 288.3 (349.9) |
Protein (g/dL) | 6.38 (0.58) | 5.40 (0.39) | 5.70 (0.34) | 5.61 (0.43) * | 5.06 (0.87) * |
Albumin (g/dL) | 3.61 (0.41) | 3.51 (0.45) | 3.55 (0.31) | 3.48 (0.40) * | 3.19 (0.65) |
Globulin (g/dL) | 2.76 (0.71) | 2.56 (0.64) | 2.40 (0.61) | 2.16 (0.48) * | 2.05 (0.59) * |
Creatinine (mg/dL) | 1.39 (0.25) | 1.63 (0.38) | 1.56 (0.35) | 1.55 (0.33) | 1.64 (0.59) |
HCT (%) | 27.25 (3.38) | 27.63 (2.13) | 27.00 (2.02) | 24.88 (2.23) * | 23.38 (3.07) * |
WBC (10^3/μL) | 11.89 (1.95) | 10.83 (1.57) | 10.51 (1.93) | 9.66 (2.52) * | 11.39 (3.02) |
Neutrophils (10^3/μL) | 6.32 (0.83) | 5.48 (0.86) | 6.05 (1.11) | 5.18 (1.73) | 6.0 (1.53) |
Lymphocytes (10^3/μL) | 3.41 (1.8) | 3.21 (0.80) | 2.64 (1.49) | 2.6 (0.84) | 3.5 (1.16) |
AST: aspartate aminotransferase; ALT: Alanine transaminase
significant change between week 0 and week 3 [time of last injection], or week 0 and week 4 (P<0.05)