TABLE 3.
Factors associated with mortality in the study patients
| Factor | Result for patients who:
|
Significance level | |
|---|---|---|---|
| Died (n = 23) | Lived (n = 131) | ||
| Mean age (yr) | 53.5 | 52.3 | NSb |
| % Female | 52.2 (12/23)a | 31.3 (41/131) | NS |
| % with underlying liver disease: | NS | ||
| Hepatitis C virus | 39.1 (9/23) | 32.1 (42/131) | |
| Alcohol | 17.4 (4/23) | 16.8 (22/131) | |
| Hepatitis C + alcohol | 8.7 (2/23) | 9.2 (12/131) | |
| Autoimmune | 17.4 (4/23) | 5.3 (7/131) | |
| Hepatitis B virus | 0 (0/23) | 6.9 (9/131) | |
| Hepatitis B + C virus | 4.3 (1/23) | 0.8 (1/131) | |
| Primary biliary cirrhosis | 4.3 (1/23) | 3.1 (4/131) | |
| Primary sclerosing cholangitis | 0 (0/23) | 8.4 (11/131) | |
| Cryptogenic | 0 (0/23) | 3.8 (5/131) | |
| Other | 8.7 (2/23) | 13.7 (18/131) | |
| % with CMV serostatus: | NS | ||
| Recipient+/donor+ | 39.1 (9/23) | 40.5 (53/131) | |
| Recipient−/donor+ | 30.4 (7/23) | 17.3 (23/131) | |
| Recipient+/donor− | 8.7 (2/23) | 26.0 (34/131) | |
| Recipient−/donor− | 21.7 (5/23) | 16.0 (21/131) | |
| % with CMV infection | 52.2 (12/23) | 42 (55/131) | NS |
| % with CMV disease | 13.0 (3/23) | 0.8 (1/131) | 0.011 |
| % with retransplantation | 0 (0/23) | 6.1 (8/131) | NS |
| % with immunosuppression | |||
| Tacrolimus | 82.6 (19/23) | 74.1 (96/131) | NS |
| Cyclosporin A | 8.7 (2/23) | 4.6 (6/131) | NS |
| Mycophenolate mofetil | 0 (0/23) | 6.1 (8/131) | NS |
| Sirolimus | 13.0 (3/23) | 10.7 (14/131) | NS |
| Thymoglobulin | 52.2 (12/23) | 40.5 (53/131) | NS |
| % with rejection | 13.0 (3/23) | 19.9 (26/131) | NS |
| % on dialysis | 60.9 (14/23) | 6.1 (8/131) | 0.0001 |
| Median length of ICU stay (days) | 37.5 | 11.5 | 0.0001 |
| % human immunodeficiency virus coinfected | 0 (0/23) | 3.8 (5/131) | NS |
| % with receipt of an antifungal agent | 43.5 (10/23) | 12.2 (16/131) | 0.0009 |
| % with false-positive test | 34.8 (8/23) | 9.2 (12/130) | 0.003 |
| No. of tests performed | 14 | 7 | 0.006 |
| No. of positive tests/100 tests | 2.91 | 1.05 | 0.032 |
a
No. with result/no. in the group.
b
NS, not significant (P > 0.05).