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Ten-year survival with combination chemotherapy versus placebo, according to nodal and age/menopausal status: results of a systematic review of RCTs (see text).
| Control (%) | Chemotherapy (%) | Absolute benefit (%) | SD (%) | Significance (two sided) | |
| Age under 50 years | |||||
| Node +ve | 41.4 | 53.8 | +12.4 | 2.4 | P <0.0001 |
| Node –ve | 71.9 | 77.6 | +5.7 | 2.1 | P = 0.01 |
| Age 50 to 69 years | |||||
| Node +ve | 46.3 | 48.6 | +2.3 | 1.3 | P = 0.001 |
| Node –ve | 64.8 | 71.2 | +6.4 | 2.3 | P = 0.0025 |
SD, standard deviation.
