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The log (k’/k’ethylbenzene) of the 16 solutes in Snyder’s phase characterization method [58] on different phases. Chromatographic conditions are the same as in Fig. 6. ■: SB C18; □: HC-C8; △: −SO3-HC-C8-L after gradient acid washing; + and dotted line: −SO3-HC-C8-H before gradient acid washing (nortriptyline and amitriptyline are strongly retained and not eluted in a reasonable time).
