Table 4.
Validation of Prop1-specific changes in gene expression
| Fold Change |
||||
|---|---|---|---|---|
| Gene Symbol | Gene Name | Microarray | qPCR | |
|
Prop1df/df |
Prop1df/df |
Prop1df/df |
||
| Pit1dw/dw | Prop1+/+ | Prop1+/+ | ||
| Sult1e1 | sulfotransferase family 1E, member 1 | 16.7 | 9.0 | 212.3 |
| Cbr2 | carbonyl reductase 2 | 19.2 | 3.6 | 14.1 |
| Adamdec1 | ADAM-like, decysin 1 | 14.9 | 8.4 | 12.9 |
| Otx2 | orthodenticle homolog 2 | 2.9 | 2.5 | 4.6* |
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 2.4 | 2.3 | 3.3* |
| Cldn10 | claudin 10 | 2.2 | 2.2 | 2.2* |
| Lbxcor1 | ladybird homeobox 1 homolog corepressor 1 | −2.3 | −2.5 | −3.3* |
| Rgs2 | regulator of G-protein signaling 2 | −4.0 | −2.1 | −4.8 |
| Cart | cocaine and amphetamine regulated transcript | −4.0 | −4.0 | −21.4 |
*
Genes with reported expression in e12.5–e14.5 mouse pituitary gland.