Table 1.
Demographic characteristics and variables stratified by anemia in VACS (n = 2462)
| Variable | Statistic | All | Nonanemic | Anemic | P |
|---|---|---|---|---|---|
| Age, y | |||||
| < 40 | n (%) | 299 (12.1) | 257 (13.0) | 42 (8.7) | .001 |
| 41-50 | 1081 (43.9) | 883 (44.6) | 198 (41.1) | ||
| 51-64 | 954 (38.7) | 749 (37.8) | 205 (42.5) | ||
| 65+ | 128 (5.2) | 91 (4.6) | 37 (7.7) | ||
| Sex | |||||
| Male | n (%) | 2332 (94.7) | 1868 (94.3) | 464 (96.3) | .091 |
| Female | 130 (5.3) | 112 (5.7) | 18 (3.7) | ||
| Race | |||||
| White | n (%) | 490 (19.9) | 451 (22.8) | 39 (8.1) | < .001 |
| Black | 1677 (68.1) | 1285 (64.9) | 392 (81.3) | ||
| Hispanic | 203 (8.2) | 171 (8.6) | 32 (6.6) | ||
| Other | 92 (3.7) | 73 (3.7) | 19 (3.9) | ||
| Mortality | |||||
| No | n (%) | 2316 (94.1) | 1882 (95.1) | 434 (90.0) | < .001 |
| Yes | 146 (5.9) | 98 (4.9) | 48 (10.0) | ||
| HIV status | |||||
| Negative | n (%) | 865 (35.1) | 753 (38.0) | 112 (23.2) | < .001 |
| Positive | 1597 (64.9) | 1227 (62.0) | 370 (76.8) | ||
| CD4, n = 1542 | n | 1542 | 1188 | 354 | < .001 |
| Mean (SD) | 421.0 (284.2) | 447.5 (284.9) | 332.3 (263.7) | ||
| Median | 371 | 400 | 287.5 | ||
| (Min, max) | (3.0, 2538) | (3.0, 2538) | (4.0, 1394) | ||
| (25th, 75th) | (221.0, 557.0) | (250.0, 584.5) | (138.0, 439.0) | ||
| HIV-1 viral load, n = 1542 | n | 1542 | 1186 | 356 | < .001 |
| Mean (SD) | 3.1 (1.2) | 3.0 (1.2) | 3.3 (1.3) | ||
| Median | 2.7 | 2.6 | 3 | ||
| (Min, max) | (1.7, 5.9) | (1.7, 5.9) | (1.7, 5.9) | ||
| (25th, 75th) | (1.9, 4.1) | (1.9, 4.0) | (1.9, 4.4) | ||
| Comorbidities | |||||
| None | n (%) | 99 (4.0) | 92 (4.6) | 7 (1.5) | < .001 |
| 1-2 conditions | 951 (38.6) | 827 (41.8) | 124 (25.7) | ||
| > 3 conditions | 1412 (57.4) | 1061 (53.6) | 351 (72.8) | ||
| cART baseline, n = 1597 | |||||
| No | n (%) | 457 (28.6) | 361 (29.4) | 96 (25.9) | .195 |
| Yes | 1140 (71.4) | 866 (70.6) | 274 (74.1) | ||
| BMI, n = 2424 | n | 2424 | 1954 | 470 | < .001 |
| Mean (SD) | 26.8 (5.3) | 27.1 (5.2) | 25.5 (5.3) | ||
| Median | 25.8 | 26.4 | 24.4 | ||
| (Min, max) | (12.6, 50.8) | (12.6, 50.8) | (13.1, 46.2) | ||
| (25th, 75th) | (23.0, 29.7) | (23.6, 30.0) | (22.0, 27.6) | ||
| Ferritin, n = 363 | |||||
| < 10 | n (%) | 2 (0.6) | 2 (0.7) | 0 (0.0) | .639 |
| 10-170 | 161 (44.4) | 130 (43.5) | 31 (48.4) | ||
| > 170 | 200 (55.1) | 167 (55.9) | 33 (51.6) | ||
| Hepcidin, n = 339 | n | 339 | 281 | 58 | .665 |
| Mean (SD) | 22.0 (17.9) | 22.4 (18.9) | 19.5 (11.6) | ||
| Median | 18.1 | 18 | 18.8 | ||
| (Min, max) | (2.3, 125.4) | (2.4, 125.4) | (2.3, 59.3) | ||
| (25th, 75th) | (10.5, 27.3) | (10.7, 28.1) | (9.9, 25.5) |
VACS indicates Veterans Aging Cohort Study; cART, combined antiretroviral therapy; and BMI, body mass index.