Table 2.
Frequency of BCR-ABL+ cells on limiting dilution and FISH analysis
| Patient | Years on IM treatment | Frequency of BCR-ABL+ cells, % |
|||
|---|---|---|---|---|---|
| Limiting dilution analysis |
FISH |
||||
| CD34+CD38+ | CD34+CD38− | CD34+CD38−* | CD34+CD38+* | ||
| 476 | 4 | 0.03 | 0.20 | ||
| 4.5 | 0.05 | 0.09 | |||
| 5.5 | 0.25 | 0.54 | 0 (200) | ||
| 469 | 2 | 0.16 | 0.81 | ||
| 3 | 0.12 | 0.34 | |||
| 397 | 2 | 0.32 | 1.06 | 0 (50) | 0 (233) |
| 3 | 0.15 | 0.47 | 0 (200) | 0 (206) | |
| 6.5 | 0.21 | 0.41 | 1 (200) | 0 (216) | |
| 273 | 4.5 | 0.27 | 1.61 | 0.5 (200) | 0 (246) |
| 6.5 | 0.17 | 0.56 | 1 (98) | 0 (220) | |
| 296 | 1 | 0.23 | 0.46 | ||
| 3 | 0.04 | 0.75 | |||
| 299 | 3 | 0.29 | 0.47 | ||
| 4 | 0.32 | 0.45 | |||
*
Numbers in parentheses represent number of cells analyzed.