Table 4.

Grade 3 or 4 AEs in 38 rel/ref cHL patients, n (%)

Characteristic	Grade 3	Grade 4	Total Grade 3 and 4
Hematologic
Neutropenia	13 (34)	5 (13)	18 (47)
Leukopenia	9 (24)	2 (5)	11 (29)
Anemia	8 (21)	2 (5)	10 (26)
Lymphopenia	7 (18)	2 (5)	9 (24)
Thrombocytopenia	5 (13)	2 (5)	7 (18)
Febrile neutropenia	1 (3)		1 (3)
Nonhematologic
Fatigue	3 (8)		3 (8)
AST	3 (8)		3 (8)
ALT	1 (3)	1 (3)	2 (5)
Bilirubin	1 (3)	1 (3)	2 (5)
Sensory neuropathy	2 (5)		2 (5)
Dehydration	2 (5)		2 (5)
Infection without neutropenia	2 (5)		2 (5)
Infection with neutropenia	1 (3)		1 (3)
Edema	2 (5)		1 (3)
Dyspnea	1 (3)		1 (3)
Pleural effusion	1 (3)		1 (3)
Alkaline phosphatase	1 (3)		1 (3)
Pain, abdominal	1 (3)		1 (3)
Metabolic/laboratory
Low potassium	2 (5)	1 (3)	3 (8)
Low sodium	1 (3)	1 (3)	2 (5)
Low albumin	1 (3)		1 (3)
Low calcium	1 (3)		1 (3)
High calcium		1 (3)	1 (3)
Low phosphorous	1 (3)		1 (3)