Table 1. Effects of beauveriolides and other compounds on CE synthesis and ACAT activity.

			ACAT
Compound	CE synthesis in macrophage	Postlysosomal cholesterol metabolism	Mouse macrophage	Mouse liver	Caco-2
Beauveriolide I	0.78	0.37	6.0	1.5	2.5
Beauveriolide III	0.41	0.21	5.5	1.5	1.0
Beauvericin	0.13	0.01	1.0	8.0	NT
Cytochalasin D	2.4	>20	NT	>100	NT
CL-283,546	0.035	0.04	0.001	0.005	0.055

IC₅₀ values stated are micromolar. NT, not tested.