Table 1. Patterns of change in serum hormone levels and Leydig cell steroidogenesis during DEHP treatment.

	Treatment period
Parameter	PND 21-48*	PND 21-90	PND 21-120
Serum hormones
LH	↑	↑	↑
T	↑	↑	↑
E2	↑	—	ND
Leydig cell steroidogenesis
T	↑	↓	↓
E2	↑	↓	ND
Number of Leydig cells in the testis	ND	↑	↑

↑, increase; ↓, decrease; —, unchanged; ND, not determined.

^*Observations from ref. 10, except E2 measurements (present study).