Table 3.
Structural magnetic resonance imaging findings
Variable | d-TGA (n=111) | Referent (n=55) | P value* |
---|---|---|---|
n (%) | |||
Any abnormality | 37 (33) | 2 (4) | <.001 |
Focal or multifocal abnormality | 26 (23) | 0 | <.001 |
Focal infarction or atrophy | 7 (6) | 0 | .10 |
Brain mineralization/iron deposit | 23 (21) | 0 | <.001 |
Diffuse abnormality | 3 (3) | 0 | .55 |
Myelination delay | 0 | 0 | - |
Ventriculomegaly | 0 | 0 | - |
Abnormal T2 hyperintensities | 3 (3) | 0 | .55 |
Generalized abnormality | 0 | 0 | - |
Developmental abnormality | 9 (8) | 2 (4) | .34 |
Major malformation | 0 | 0 | - |
Minor malformation† | 9 (8) | 2 (4) | .34 |
Values are counts and percentages.
Determined by Fisher’s exact tests.
Minor malformations include Chiari malformation (n=2), arachnoid cyst, cerebellar tonsillar ectopia, enlarged empty sella, enlarged perivascular space in right parietal lobe, gray matter heterotopia in right frontal lobe, right thalamic signal abnormality (possible gliosis vs. low grade tumor), and small right hippocampus in d-TGA group; and Chiari malformation and developmental venous anomaly in right parietal lobe in referent group.