Skip to main content
. Author manuscript; available in PMC: 2013 Jan 2.
Published in final edited form as: Mol Cell Endocrinol. 2011 Sep 22;348(1):331–338. doi: 10.1016/j.mce.2011.09.032

Fig. 5. JNK kinase activity is required for Ral-dependent activation of the native MMP1 and PRUNE genes.

Fig. 5

HeLa-ERα cells were treated with SP for 1 hour prior to a 3 hour treatment with Ral (100 nM) or E2 (100 nM), as indicated. The cells were collected and subjected to RT-qPCR expression analyses, and the results were standardized to β-actin. Each bar represents the mean ± SEM for n ≥ 3 separate experiments. White bars marked with a single asterisk are significantly different from the corresponding “Veh” controls (Student’s t-test, p < 0.05). Black bars marked with two asterisks are significantly different from the corresponding “−SP” controls for that particular treatment (Student’s t-test, p < 0.05).