| Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
| Adverse effects | |||||
|
RCT |
60 people with any severity of acute or chronic diffuse otitis externa on otoscopy, in a primary-care setting |
Local stinging or burning in first few days of treatment
6/32 (19%) with neomycin–dexamethasone–acetic acid spray 3/26 (12%) with framycetin–gramicidin–dexamethasone drops |
Significance not assessed |