Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Healing rates
Systematic review	22 people Data from 1 RCT	Mean time to reach 50% reduction in initial wound volume with topical negative pressure with gauze soaked in Ringer's solution Absolute results not reported	Mean difference –1.00 days 95% CI –0.82 days to +6.21 days		Not significant
Systematic review	35 people Data from 1 RCT	Wound surface reduction 51.8% with topical negative pressure 42.1% with regimen of three gel products Absolute numbers not reported	P = 0.46		Not significant