Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Healing rates
RCT	48 people In review	Mean time to healing 35.3 days with topical phenytoin suspension (100 mg capsule in 5 mL saline) 51.8 days with hydrocolloid dressings or antibiotic ointment	P <0.005	Effect size not calculated	topical phenytoin suspension
RCT 3-armed trial	83 people In review	Complete ulcer healing 11/28 (39%) with topical phenytoin 20/28 (71%) with hydrocolloid dressings	ARR 32% 95% CI 7.4% to 56.7%	Effect size not calculated	topical phenytoin
RCT 3-armed trial	83 people In review	Complete ulcer healing 11/28 (39%) with topical phenytoin 8/27 (30%) with standard dressings	P value not reported
Systematic review	28 people, mean age 31 to 34 years, rehabilitation, trial duration 2 weeks, grade II ulcers Data from 1 RCT	Mean reduction in Pressure Ulcer Scale for Healing (PUSH) scores 2 weeks 19.53 with phenytoin solution 11.39 with normal saline	P = 0.26		Not significant