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. 2011 Nov 16;6(11):e26797. doi: 10.1371/journal.pone.0026797

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Hengenius et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Simulation results in the 3D model. (A–H) Lateral view of VE geometry is shown in rows A–G (Gt, Hb, Kni, Kr, Tll at t = 70 min, Cad at t = 56 min); row H displays RMSE difference between model and VE data summed with all time points. Column 1 shows scaled VE data. Column 2 displays output from evaluated with GRN . Column 3 contains output from incorporating DV-asymmetric Bcd data and GRN ; Column 4 illustrates the effect of the smoothed Bcd interpolant in while considering the same GRN . Column 5 displays output from with reoptimized parameters . White boxes indicate the lateral areas where Jaeger et al. optimized their 1D model. Animations of pattern development are available for column 2 ( , Movies S1, S2, S3, S4, S5, S6) and column 5 (, Movies S7, S8, S9, S10, S11, S12) in the supplementary material.

Inline graphic — Simulation results in the 3D model. (A–H) Lateral view of VE geometry is shown in rows A–G (Gt, Hb, Kni, Kr, Tll at t = 70 min, Cad at t = 56 min); row H displays RMSE difference between model and VE data summed with all time points. Column 1 shows scaled VE data. Column 2 displays output from evaluated with GRN . Column 3 contains output from incorporating DV-asymmetric Bcd data and GRN ; Column 4 illustrates the effect of the smoothed Bcd interpolant in while considering the same GRN . Column 5 displays output from with reoptimized parameters . White boxes indicate the lateral areas where Jaeger et al. optimized their 1D model. Animations of pattern development are available for column 2 ( , Movies S1, S2, S3, S4, S5, S6) and column 5 (, Movies S7, S8, S9, S10, S11, S12) in the supplementary material.