Table 2. Factors Associated with TB-Treatment Adverse Effects.
Variable | Cases | Controls | p value | Crude Model | Adjusted Model* |
n (%) | n (%) | OR (95%CI) | OR (95%CI) | ||
Sex | |||||
Female | 55 (38.2) | 217 (37.7) | 0.91 | 1 | – |
Male | 89 (61.8) | 359 (62.3) | 0.98 (0.67–1.42) | – | |
Age | |||||
<20 years | 19 (13.2) | 142 (24.7) | 0.003 | 1 | – |
20–39 years | 77 (53.5) | 303 (52.6) | 1.90 (1.11–3.26) | – | |
40+ years | 48 (33.3) | 131 (22.7) | 2.74 (1.53–4.90) | – | |
Alcohol Use | |||||
No | 90 (64.3) | 428 (75.5) | 0.007 | 1 | 1 |
Yes | 50 (35.7) | 139 (24.5) | 1.71 (1.15–2.54) | 1.80 (1.16–2.80) | |
Anemia | |||||
No | 82 (69.5) | 323 (81.4) | 0.006 | 1 | 1 |
Yes | 36 (30.5) | 74 (18.6) | 1.92 (1.20–3.05) | 2.29 (1.37–3.83) | |
Body Mass Index | |||||
Normal | 69 (57.5) | 319 (69.7) | 0.02 | 1 | 1 |
BMI≥25 kg/m2 | 37 (30.8) | 89 (19.4) | 1.92 (1.21–3.05) | 1.72 (1.04–2.84) | |
BMI<18.5 kg/m2 | 14 (11.7) | 50 (10.9) | 1.29 (0.68–2.47) | 1.35 (0.68–2.68) | |
Diabetes Mellitus †† | |||||
No | 126 (92.7) | 526 (96.7) | 0.05 | 1 | 1 |
Yes | 10 (7.4) | 18 (3.3) | 2.32 (1.05–5.15) | 1.33 (0.54–3. 24) | |
HIV Infection †† | |||||
No | 124 (89.2) | 545 (97.0) | <0.001 | 1 | 1 |
Yes | 15 (10.8) | 17 (3.0) | 3.88 (1.89–7.98) | 3.45 (1.61–7.45) | |
MDR-TB | |||||
No | 74 (51.4) | 529 (91.8) | <0.001 | 1 | 1 |
Yes | 70 (48.6) | 47 (8.2) | 10.7 (6.84–16.6) | 10.3 (6.39–16.5) | |
Tobacco use | |||||
No | 90 (64.3) | 428 (75.5) | 0.102 | 1 | 1 |
Yes | 50 (35.7) | 139 (24.5) | 1.50 (0.92–2.45) | 1.65 (0.97–2.81) |
*Adjusted for age, sex and year of diagnosis.
Association evaluated by Fisher's Exact Test.
Data might not add up to totals due to missing values.