Skip to main content
. 2011 Nov 16;6(11):e27610. doi: 10.1371/journal.pone.0027610

Table 2. Factors Associated with TB-Treatment Adverse Effects.

Variable Cases Controls p value Crude Model Adjusted Model*
n (%) n (%) OR (95%CI) OR (95%CI)
Sex
Female 55 (38.2) 217 (37.7) 0.91 1
Male 89 (61.8) 359 (62.3) 0.98 (0.67–1.42)
Age
<20 years 19 (13.2) 142 (24.7) 0.003 1
20–39 years 77 (53.5) 303 (52.6) 1.90 (1.11–3.26)
40+ years 48 (33.3) 131 (22.7) 2.74 (1.53–4.90)
Alcohol Use
No 90 (64.3) 428 (75.5) 0.007 1 1
Yes 50 (35.7) 139 (24.5) 1.71 (1.15–2.54) 1.80 (1.16–2.80)
Anemia
No 82 (69.5) 323 (81.4) 0.006 1 1
Yes 36 (30.5) 74 (18.6) 1.92 (1.20–3.05) 2.29 (1.37–3.83)
Body Mass Index
Normal 69 (57.5) 319 (69.7) 0.02 1 1
BMI≥25 kg/m2 37 (30.8) 89 (19.4) 1.92 (1.21–3.05) 1.72 (1.04–2.84)
BMI<18.5 kg/m2 14 (11.7) 50 (10.9) 1.29 (0.68–2.47) 1.35 (0.68–2.68)
Diabetes Mellitus ††
No 126 (92.7) 526 (96.7) 0.05 1 1
Yes 10 (7.4) 18 (3.3) 2.32 (1.05–5.15) 1.33 (0.54–3. 24)
HIV Infection ††
No 124 (89.2) 545 (97.0) <0.001 1 1
Yes 15 (10.8) 17 (3.0) 3.88 (1.89–7.98) 3.45 (1.61–7.45)
MDR-TB
No 74 (51.4) 529 (91.8) <0.001 1 1
Yes 70 (48.6) 47 (8.2) 10.7 (6.84–16.6) 10.3 (6.39–16.5)
Tobacco use
No 90 (64.3) 428 (75.5) 0.102 1 1
Yes 50 (35.7) 139 (24.5) 1.50 (0.92–2.45) 1.65 (0.97–2.81)

*Adjusted for age, sex and year of diagnosis.

††

Association evaluated by Fisher's Exact Test.

Data might not add up to totals due to missing values.