Table 1. Key HIV screening parameters.
Parameter | Value | Range | Source |
Proportion tested in past 12 months (status quo) | |||
High-risk individuals | 23% | 10–30% | [44] |
Low-risk individuals | 10% | 5–20% | [44] |
Symptom-based case finding per year | |||
Symptomatic HIV | 10% | 0–30% | [35] |
AIDS | 20% | 10–60% | [35] |
Window period of detection (days) | |||
3rd generation ELISA | 22 | 14–40 | [6], [7], [10] |
4th generation immunoassay | 17 | 10–28 | [6], [18] |
NAAT | 11 | 9–30 | [6], [11] |
NAAT pooling algorithm sensitivity | 95% | 90–100% | [39] |
NAAT pooling efficiency (tests/specimen) | 0.11 | 0.10–1.0 | [2], [39] |
Proportion tested who receive NAAT test results | 80% | 50–100% | [17] |
Reduction in sexual partners if identified | 50% | 20–70% | [8], [9], [45] |
Cost of 3rd-generation ELISA | $15 | $10–$25 | [11], [35], [43], [46], [47] |
Cost of Western Blot confirmatory test | $40 | $25–$50 | [47] |
Cost of NAAT | $120 | $100–$150 | [11]–[14], [39], [46] |
Cost of quantitative viral load assay | $120 | $100–$140 | [48], [49] |
Cost of HIV counseling | $60 | $40–$100 | [35], [42], [43] |
ELISA = enzyme linked immunosorbent assay; NAAT = nucleic acid amplification test.