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. 2011 Nov 16;6(11):e27603. doi: 10.1371/journal.pone.0027603

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Lefkowitz et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Phenotypic association of genes expressed in the hair shaft library. Shown are numbers of genes present in the hair shaft that are associated with organ phenotypes identified by mouse mutations. (B) Environmental exposures pathways associated with genes identified in hair shaft library. Numbers of genes associated with selected exposure pathways are shown. (C) Disorder pathways associated with genes present in hair shaft library. (D) Compound pathways associated with hair shaft RNA library. Gray shading of column bars in all panels indicates lower limits of p-values calculated based on input hair shaft library genes vs. random background genes. Red solid circles denote unique pathway gene sets identified in hair shaft but not keratinocytes.