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. 2011 Nov 16;6(11):e27758. doi: 10.1371/journal.pone.0027758

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Kanda et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Schematic representation of the various repetitive sequences within the EBV genome. Internal repeats (IR) 1 to 4 are indicated [3]. The oriP region (spanning the FR region), the oriLyt regions [18], and the region deleted in the B95-8-strain EBV (spanning the region of IR4 and the right oriLyt) are also indicated. (B) Restriction enzyme maps of the B95-8 and the Akata oriP regions. The 252-bp sequence that is missing in the B95-8 sequence (V01555) is indicated in gray within the B95-8 oriP. The position of the 128-bp palindromic sequence is also indicated. The numbering of the base pairs corresponds to the B95-8 sequence (V01555), except for the addition of 252 bp in the downstream region of the FR.