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. 2011 Nov 16;6(11):e27958. doi: 10.1371/journal.pone.0027958

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Gurung et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A to D) Transmission electron micrograph of MVs prepared from S. aureus ATCC 25923 (A), ATCC 700699 (B), 103D (C), and 06ST1048 (D) cultured in LB broth. (E and F) Production and secretion of MVs from S. aureus 06ST1048 during in vivo infection. Neutropenic mice were infected with 1×10⁷ CFU of bacteria intratracheally. The S. aureus-infected mice were sacrificed 18 h after bacterial injection. Arrows indicate the spherical nanovesicles from S. aureus.