Figure 2. Increased number and rate of papilloma formation in Gstp−/−/Tg.AC mice.
(a) Papilloma incidence (number of mice with at least one papilloma) and (b) multiplicity (mean number of papillomas per mouse) was determined twice-weekly over a 15-week period in Gstp−/−/Tg.AC (circles) and Gstp+/+/Tg.AC mice (triangles). n=29 wt, 33 null at experimental initiation, (* p<0.05, ** p<0.01, *** p<0.001). Data are mean + standard deviation.