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. Author manuscript; available in PMC: 2012 May 15.
Published in final edited form as: Cancer Res. 2011 Oct 5;71(22):7048–7060. doi: 10.1158/0008-5472.CAN-11-0882

Figure 3. Increased skin thickness, but no change in BrdU labelling, in Gstp−/−/Tg.AC mice treated with TPA for 6 weeks.

Figure 3

(a) Increase in skin thickness relative to acetone controls in both Gstp+/+/Tg.AC (compare i and iii) and Gstp−/−/Tg.AC mice (compare ii and iv) following TPA treatment, whilst comparison of iii and iv clearly shows the increased thickness of the epidermal layer in Gstp−/−/Tg.AC mice relative to Gstp+/+/Tg.AC mice. *** p<0.001; 6 fields/slide, 5 measurements/field; n=3, (b) Skin thickness in Gstp+/+/Tg.AC (black bars) and Gstp−/−/Tg.AC (white bars) mice following TPA treatment, (c) No difference in BrdU-labelled cells between Gstp+/+/Tg.AC mice and Gstp−/−/Tg.AC mice. Sections shown are representative of each genotype (3 fields/slide, n= 3 for each genotype).