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(A) Model of amelogenin molecule consists of a spherical colloid particle and a point charge located on its surface that preserves a bipolar nature. (B and C) Oligomerization of amelogenin molecules occurs by means of hydrophobic interactions and modification due to Coulomb repulsions. (D) Nanosphere structures are formed through aggregation of monomers and oligomers. (E) Further association of nanospheres results in larger assemblies among which chains are formed. (Color online).
