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Hippocampal neurodegeneration after CCI with a flat-tip (A, C, E) or a rounded- tip (B, D, F) impactor. Fluorojade-B staining of sections taken at the impact epicenter illustrate degenerating neurons in the dentate gyrus granule layers, dentate hilus, and CA3 and CA1 pyramidal layers at 4 h (A, B), 12 h (C, D), and 24 h (E, F) after 1.0-mm CCI brain injury. Scale bar represents 500 μm.
