Figure 2.

Antiproliferative effects of Mito-CP₁₁ and CP in MCF-7 and MCF-10A cells. (A) MCF-7 and MCF-10A cells were treated with Mito-CP₁₁ and CP (0.5 and 1 µM) for 48 h, and colonies formed were counted after 5 d (for MCF-7 cells) and 7 d (for MCF-10A cells). (B) The cell survival fractions calculated as described in the Materials and Methods section in Mito-CP₁₁- and CP-treated MCF-7 and MCF-10A cells are shown. The plating efficiency calculated for MCF-7 and MCF-10A cells was 65 ± 13 and 38 ± 5, respectively. The error bars represent standard deviation and * symbol indicates a p value of less than 0.02 as determined by Student's t-test (n = 5).