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. Author manuscript; available in PMC: 2012 Sep 13.
Published in final edited form as: Circulation. 2011 Sep 13;124(11 Suppl):S35–S45. doi: 10.1161/CIRCULATIONAHA.111.035774

Figure 5.

Figure 5

Primary cultures of sheep LV myocardial fibroblasts were plated on the vehicle utilized for CHAM delivery, CHAM or in untreated culture dishes. TOP- low power views of the confluent LV fibroblast cultures and high power views demonstrating the typical morphometry and growth patterns. While plating LV fibroblasts on vehicle or CHAM did not appear to alter MMP/TIMP mRNA levels, collagen I and III as well as transforming growth factor-beta (TGF-B1) increased in the CHAM groups. All experiments performed in triplicate; * p<0.05 vs control, # p<0.05 vs vehicle.