Table 1.

LV geometry, function, infarct thickness and myocardial collagen content at eight weeks post-MI; Effects of CHAM

	LV EDV (mL)	LV EF (%)	MI Thickness (mm)	MI Size (% LV)	Collagen Content (μg/mg wet weight)
					MI	BZ	Remote
Control	52.9±3.0	52.1±1.3	6.08±0.34#	N/A	8.5±1.1
MI Only	105.4±7.5*	20.9±2.3*	2.69±0.23*	24.7±1.2	113.1±13.8*	11.5±2.5	9.2±1.5
1.3 mL CHAM	94.5±5.0*	26.8±1.5*	5.48±0.34‡	27.1±0.8	73.1±8.9*‡	18.1±4.6	7.1±0.7
2.6 mL CHAM	80.6±4.2*‡	37.2±3.7*‡§	5.44±0.15‡	24.7±1.0	84.9±9.9*	14.7±4.8	6.7±0.8

Values are means±SEM;

LVEDV = Left ventricle end diastolic volume, LV EF = Left ventricle ejection fraction.

^#posterior wall thickness; BZ: Border zone

Sample sizes: Referent Control n=6, MI Only n=13, 1.3 mL CHAM n=6, 2.6 mL CHAM n=5

^*p<0.05 vs. Referent Control

^‡p<0.05 vs. MI Only

^§p<0.05 vs. 1.3 mL CHAM