Table 3.

Levels of myocardial TIMPs at eight weeks after MI; Effects of biocomposite microsphere injection

	Referent Control	Region	MI Only	CHAM#
				1.3 mL	2.6 mL
TIMP-1 (IOD, pixels)	180 ± 42	MI	12 ± 2*	5 ± 2*	5 ± 2*
		BZ	557 ± 102	617 ± 182	572 ± 121
		Remote	786 ± 113*	939 ± 87*	483 ± 58*
TIMP-2 (IOD, pixels)	252 ± 29	MI	63 ± 22*	98 ± 29*	153 ± 67*
		BZ	200 ± 74	365 ± 123	927 ± 460
		Remote	445 ± 157	1135 ± 442	963 ± 422
TIMP-4 (IOD, pixels)	977 ± 64	MI	323 ± 113*	336 ± 225*	389 ± 306
		BZ	1102 ± 143	977 ± 187	1008 ± 227
		Remote	1267 ± 109	1337 ± 67	1167 ± 99

Values presented as mean±SEM.

^*p<0.05 vs. referent control.

^#= calcium hydroxyapatite microspheres (CHAM); IOD: Integrated optical density; BZ: Border zone

Sample sizes: Referent Control n=6, MI Only n=13, 1.3 mL n=6, 2.6 mL n=5