Table 1.
Sample | Polymer | Theoretical drug loading | Size (nm) | PDI | ZP (mV) | EE (%) |
---|---|---|---|---|---|---|
ANP | PCL-Tween 80 | 10% | 204.95 ± 3.66 | 0.201 ± 0.23 | −20.14 ± 0.15 | 81.98 ± 2.61 |
BNP | PCL-Tween 80 | 0 | 192.45 ± 1.93 | 0.163 ± 0.17 | −18.33 ± 0.31 | 0 |
CNP | PCL-Tween 80 | * | 217.36 ± 2.02 | 0.241 ± 0.09 | −22.25 ± 0.29 | Not shown |
DNP | PCL | 10% | 258.48 ± 5.95 | 0.301 ± 0.15 | −13.55 ± 0.19 | 71.44 ± 3.61 |
ENP | PCL | * | 223.33 ± 3.33 | 0.236 ± 0.31 | −16.26 ± 0.22 | Not shown |
Note: Coumarin 6.
Abbreviations: PDI, polydispersity index; ZP, zeta potential; EE, encapsulation efficiency; ANP, PCL-Tween 80 nanoparticles; DNP, docetaxel-loaded PCL nanoparticles; BNP, drug-free PCL-Tween 80 nanoparticles; ENP, coumarin 6-loaded PCL nanoparticles; CNP, coumarin 6-loaded PCL-Tween 80 nanoparticles.